ESTROGEN-RECEPTORS IN CONJUNCTIVAL MALIGNANT-MELANOMA - IMMUNOCYTOCHEMICAL STUDY USING FORMALIN FIXED PARAFFIN WAX SECTIONS

被引：19
|
作者：
PARIDAENS, DA
ALEXANDER, RA
HUNGERFORD, JL
MCCARTNEY, ACE
机构：
[1] DEPT PATHOL,17-25 CAYTON ST,LONDON EC1V 9AT,ENGLAND
[2] INST OPHTHALMOL,LONDON,ENGLAND
[3] MOORFIELDS EYE HOSP,LONDON WC1V 7AN,ENGLAND
来源：
JOURNAL OF CLINICAL PATHOLOGY | 1991年 / 44卷 / 10期
关键词：
D O I：
10.1136/jcp.44.10.840
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
In a group of 15 women with conjunctival malignant melanoma six cases (40%) were shown to have oestrogen receptor positivity using a monoclonal antibody to oestrogen receptor related antigen (ER-D5, Amersham RPN.710) on formalin fixed, paraffin wax sections. Receptors were also present in the epithelium of these six cases but not in controls and cases without ER-D5 positivity in their tumours. A subset of these aggressive, intractable unilateral tumours may therefore be amenable to hormone treatment.
引用
收藏
页码：840 / 843
页数：4
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