SUBUNIT INTERACTIONS IN PIG-HEART FUMARASE .1. STUDY OF TETRAMER DIMER EQUILIBRIUM IN DILUTE UREA SOLUTIONS

被引:5
|
作者
BEECKMANS, S [1 ]
KANAREK, L [1 ]
机构
[1] VRIJE UNIV BRUSSEL, B-1640 ST GENESIUS RODE, BELGIUM
来源
INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1982年 / 14卷 / 11期
关键词
D O I
10.1016/0020-711X(82)90056-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Information about the interaction forces at the contact regions between fumarase subunits is obtained from kinetic and structural studies of dissociation and reassociation. In dilute urea solutions an equilibrium between tetramers and dimers is established. No appreciable unfolding of the individual subunits is observed in these conditions.
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页码:965 / 970
页数:6
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