SYNTHESIS OF FLUORO-DIDEUTERO-METHYL 1,1,1,3,3,3-HEXAFLUORO-2-PROPYL ETHER (DEUTERATED SEVOFLURANE)

被引:7
|
作者
BAKER, MT
CHIANG, CK
TINKER, JH
机构
[1] Department of Anesthesia, University of Iowa, Iowa City, Iowa
关键词
SEVOFLURANE; DEUTERATION; FLUORINATION;
D O I
10.1002/jlcr.2580330902
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Sevoflurane was synthesized with deuterium substituents on the fluoromethoxy carbon. This was performed by a two-step reaction process that yielded deuterated sevoflurane of high purity.
引用
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页码:801 / 807
页数:7
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