THIOL-FATTY ACYLATION OF THE GLUCOSE-TRANSPORT PROTEIN OF HUMAN ERYTHROCYTES

被引：10
|
作者：
MAY, JM
机构：
[1] Diabetes Research and Training Center, Department of Medicine, Vanderbilt University School of Medicine, Nashville
来源：
FEBS LETTERS | 1990年 / 274卷 / 1-2期
关键词：
Erythrocyte; human; Glucose transport protein; Palmitylation; Thiol-fatty acylation;
D O I：
10.1016/0014-5793(90)81344-N
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Incubation of intact human erythrocytes with [3H]palmitate labeled a protein with electrophoretic characteristics of the glucose transporter. This labeling occurred via a thioester linkage, since it was unaffected by organic solvent extraction, but was substantially removed as the hydroxamate upon treatment with neutral hydroxylamine. Immunoprecipitation of the labeled protein with a monoclonal antibody to the glucose transporter confirmed its identity. © 1990.
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页码：119 / 121
页数：3
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