EXPERIMENTS DIRECTED TOWARDS THE SYNTHESIS OF ANTHRACYCLINONES .19. ELABORATION OF 2-FORMYLQUINIZARIN THROUGH A WITTIG REACTION

被引：2
|
作者：
BONIFACE, PJ [1 ]
CAMBIE, RC [1 ]
CARROLL, DR [1 ]
MARSH, NF [1 ]
MILBANK, JBJ [1 ]
RUTLEDGE, PS [1 ]
WOODGATE, PD [1 ]
机构：
[1] UNIV AUCKLAND,DEPT CHEM,PRIVATE BAG 92019,AUCKLAND,NEW ZEALAND
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 1994年 / 47卷 / 03期
关键词：
D O I：
10.1071/CH9940441
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of 2-formylquinizarin dimethyl ether (3) with the dimethoxy ylide (6) gives an alpha,beta-unsaturated ester (8) which on hydrogenation, reduction and methylation gives the tetramethoxyanthracene diester (18). When linked to work by Dotz and Popall this sequence provides a route to (+/-)-4-demethoxydaunomycinone.
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页码：441 / 449
页数：9
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