A spindle cell sarcoma involving the left kidney was diagnosed in a 14-year-old male Basenji. Radiography and ultrasonography were used to define the extent and location of the mass. Metastatic disease was not detected. An 8 X 5-cm mass, involving the left kidney, was resected by performing nephroureterectomy. Signs of metastasis were not detected at 3 and 6 months after surgery. Shortly after the 6-month examination, the dog was euthanatized because of perceived signs of pain attributable to cervical disk disease. Post-mortem examination was not performed. Histologic examination consisted of use of hematoxylin and eosin, Masson trichrome, and van Gieson stains, and 4 immunoperoxidase techniques. On the basis of the histologic findings, the final diagnosis was spindle cell sarcoma, with the 2 most likely possibilities being leiomyosarcoma and fibrosarcoma.