REACTION OF INDAN-1,3-DIONE WITH INDOLE, INDOLE-DERIVATIVES AND OTHER HETEROCYCLES

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作者：
HAMMOUDA, M
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来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1993年 / 32卷 / 11期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of indan-1,3-dione(1) with indole, 2-phenylindole, antipyrine, 4-aminoantipyrine and 3-amino-1-phenylpyrazol-2-in-5-one afford 2a,b,3 and 4a,b, respectively. Treatment of 2a, 3 and 4a with hydrazoic acid, under Schmidt reaction conditions, give the 4-substituted carbostyriles 5a,b and 6 respectively. Alkylation of 1 with gramine methosulfate and skatyl bromide afford 8 and 10, respectively. Condensation of 1 with 3-formylindole afford 11 which on treatment with dimethylamine furnish the gramine derivative (12).
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页码：1181 / 1184
页数：4
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