CRYSTALLIZATION OF THE FAB FRAGMENTS OF ANTIPEPTIDE MONOCLONAL-ANTIBODIES AND A COMPLEX WITH PEPTIDE

被引：3
|
作者：
GRIEST, RE [1 ]
JEFFREY, PD [1 ]
TAYLOR, GL [1 ]
REES, AR [1 ]
机构：
[1] LAB MOLEC BIOPHYS,OXFORD OX1 3QU,ENGLAND
来源：
JOURNAL OF MOLECULAR BIOLOGY | 1992年 / 223卷 / 01期
关键词：
CRYSTALLIZATION; LYSOZYME; ANTIBODIES; PEPTIDE ANTIGEN; FAB FRAGMENTS;
D O I：
10.1016/0022-2836(92)90740-B
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The antigen-binding fragments of four monoclonal antibodies that cross-react with both the "loop" peptide of hen egg-white lysozyme (residues 57 to 84) against which they were raised, and with the native protein (HEL) have been crystallized. One of these fragments also crystallizes as a complex with the peptide antigen. © 1992.
引用
收藏
页码：381 / 382
页数：2
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