IMPORTANCE OF ELEVATED PLASMA HOMOCYSTEINE LEVELS AS A RISK FACTOR FOR ATHEROSCLEROSIS

被引：23
|
作者：
MASSER, PA [1 ]
TAYLOR, LM [1 ]
PORTER, JM [1 ]
机构：
[1] OREGON HLTH SCI UNIV,DIV VASC SURG,PORTLAND,OR 97201
来源：
ANNALS OF THORACIC SURGERY | 1994年 / 58卷 / 04期
关键词：
D O I：
10.1016/0003-4975(94)90522-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Atherosclerosis is a leading cause of death and disability in the Western world, and an important risk factor for it may be an elevated level of the plasma amino acid homocysteine. The biochemical characteristics of homocysteine, along,vith historical, laboratory, and clinical evidence for its pathologic role in atherosclerosis, are reviewed. Possible therapies for reducing elevated hemocysteine levels and the possible impact of therapy in atherosclerosis are examined.
引用
收藏
页码：1240 / 1246
页数：7
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