PRELIMINARY CRYSTALLOGRAPHIC ANALYSIS OF CARDIOTOXIN-V WITH MAJOR FUSION ACTIVITY FROM TAIWAN COBRA (NAJA-NAJA-ATRA) VENOM

被引:2
|
作者
CHEN, CJ
ROSE, J
HSIAO, CD
LEE, TJ
WU, WG
WANG, BC
机构
[1] UNIV PITTSBURGH, DEPT CRYSTALLOG, PITTSBURGH, PA 15260 USA
[2] UNIV PITTSBURGH, DEPT BIOL SCI, PITTSBURGH, PA 15260 USA
[3] ACAD SINICA, INST MOL BIOL, CRYSTALLOG LAB, TAIPEI 11529, TAIWAN
[4] NATL TSING HUA UNIV, INST LIFE SCI, HSINCHU 30043, TAIWAN
关键词
CRYSTALS; CARDIOTOXIN; COBRA; VENOM; FUSION ASSAY;
D O I
10.1016/0022-2836(91)90653-N
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Crystals of a cardiotoxin from Taiwan cobra venom have been obtained by the vapor diffusion method using methyl pentanediol as precipitant. The crystals belong to the hexagonal space group P6122 (or P6522), with cell dimensions a = b = 47.5 A ̊, c = 111.3 A ̊, α = β = 90 ° and γ = 120 ° and diffract to a resolution of 2.2 Å. There is one molecule per asymmetric unit and the solvent content is estimated to be 53%. © 1991.
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页码:591 / 592
页数:2
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