PANCREATIC-SECRETION IN MAN - EFFECT OF FASTING, DRUGS, PANCREATIC-ENZYMES, AND SOMATOSTATIN

被引：0
|
作者：
ANAND, BS [1 ]
GOODGAME, R [1 ]
GRAHAM, DY [1 ]
机构：
[1] VET AFFAIRS MED CTR,DIGEST DIS SECT,HOUSTON,TX
来源：
AMERICAN JOURNAL OF GASTROENTEROLOGY | 1994年 / 89卷 / 02期
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中图分类号：
R57 [消化系及腹部疾病];
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摘要：
The inhibitory effect of different drugs on pancreatic secretions was assessed in a patient with a posttraumatic pancreatic-cutaneous fistula. The various drugs examined were: pancreatic enzymes, cimetidine, verapamil, propantheline, acetazolamide, and somatostatin analog octreotide. Only fasting and octreotide reduced pancreatic secretion. The optimum dose of octreotide was 50 mu g bid given subcutaneously; increasing the dose up to 100 mu g tid had no additional benefit. A stable pancreatic-cutaneous fistula is an excellent model to assess the effect of different therapeutic measures on pancreatic secretion.
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页码：267 / 270
页数：4
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