SELECTION OF A FLUOROQUINOLONE-CLASS DISK FOR SUSCEPTIBILITY TESTS

被引:0
|
作者
BARRY, AL [1 ]
FUCHS, PC [1 ]
机构
[1] ST VINCENT HOSP & MED CTR, PORTLAND, OR USA
来源
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A study was conducted to select a fluoroquinolone disk that could be used to represent other members of the fluoroquinolone class of drugs for routine susceptibility testing in the laboratory. Eight different fluoroquinolone agents were tested by disk diffusion and broth microdilution methods using 185 bacterial isolates, including 60 Enterobacteriaceae, 50 Pseudomonas species, 45 other gram-negative bacilli, and 30 Staphylococcus aureus. False-susceptible and false-resistant test results occurred at rates of 0-10% when disks containing different agents were tested against this unusually resistant collection of isolates. Much lower error rates would be expected with the type of microorganisms routinely encountered in clinical laboratories. Pefloxacin, enoxacin, or ciprofloxacin disks were not useful as class representatives. However, amifloxacin, lomefloxacin, ofloxacin, temafloxacin, or fleroxacin disks could be used to represent the other fluoroquinolones for routine susceptibility testing with a minimal chance of incurring serious errors.
引用
收藏
页码:17 / 22
页数:6
相关论文
共 50 条