CDNA CLONING AND SEQUENCE-ANALYSIS OF THE HUMAN A3-ADENOSINE RECEPTOR

被引：78
|
作者：
SAJJADI, FG [1 ]
FIRESTEIN, GS [1 ]
机构：
[1] GENSIA INC,11025 ROSELLE ST,SAN DIEGO,CA 92121
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1179卷 / 01期
关键词：
ADENOSINE RECEPTOR; A3; CDNA CLONING; (HUMAN);
D O I：
10.1016/0167-4889(93)90077-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report the cloning of the cDNA encoding the homolog of the A3 adenosine receptor (A3AR) from a human heart library. The receptor shares a surprisingly low degree of sequence homology to the rat A3AR. Northern analysis of various human tissues showed the human A3AR gene to be expressed primarily in lung, liver, kidney and heart, with very little expression in the brain or in skeletal muscle.
引用
收藏
页码：105 / 107
页数：3
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