OROFACIAL PAIN SENSITIVITY IN ADULT-RATS FOLLOWING NEONATAL INFRAORBITAL NERVE TRANSECTION

被引：9
|
作者：
KLEIN, BG
MISRA, BR
WHITE, CF
机构：
[1] Department of Biomedical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Insitute, Blacksburg
来源：
BEHAVIOURAL BRAIN RESEARCH | 1991年 / 46卷 / 02期
关键词：
FORMALIN TEST; OROFACIAL PAIN; INFRAORBITAL NERVE; TRIGEMINAL; NEONATAL LESION; RAT;
D O I：
10.1016/S0166-4328(05)80113-5
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
A modification of the formalin test was used to assess orofacial pain sensitivity in adult rats that received infraorbital nerve transection at birth. Normal and neonatally lesioned adult animals received an injection of either 5% formalin or saline vehicle into the whiskerpad and the duration of whiskerpad rubbing was observed for 45 min. Normal rats given formalin exhibited the previously reported biphasic pattern of rubbing. Neonatally lesioned rats given formalin did not exhibit this pattern, and were indistinguishable from either of the saline control groups.
引用
收藏
页码：197 / 201
页数：5
相关论文
共 50 条
  • [1] Widespread enhancement of pain sensitivity in MRL/MpJ mice following infraorbital nerve transection
    楼国东
    [J]. 中国药理学与毒理学杂志, 2012, 26 (03) : 444 - 444
  • [2] Involvement of glia in orofacial abnormal pain following trigeminal nerve transection in rats
    Ogawa, Akiko
    Suzuki, Ikuko
    Shima, Asako
    Honda, Kuniya
    Yamamoto, Masahiro
    Shiga, Yoshi
    Hanzawa, Naoki
    Iwata, Koichi
    [J]. PAIN RESEARCH, 2007, 22 (03) : 115 - 121
  • [3] A crucial role of HMGB1 in orofacial and widespread pain sensitization following partial infraorbital nerve transection
    Hu, Ting-Ting
    Yu, Jie
    Liu, Keyue
    Du, Yu
    Qu, Feng-Hui
    Guo, Fang
    Yu, Li-Na
    Nishibori, Masahiro
    Chen, Zhong
    Zhang, Shi-Hong
    [J]. BRAIN BEHAVIOR AND IMMUNITY, 2020, 88 : 114 - 124
  • [4] Involvement of GABAergic interneurons in orofacial neuropathic pain following trigeminal nerve transection in rats
    Okada-Ogawa, Akiko
    Suzuki, Ikuko
    Nakaya, Yuka
    Kobayashi, Masayuki
    Ebihara, Katsuko
    Imamura, Yoshiki
    Iwata, Koichi
    [J]. PAIN RESEARCH, 2013, 28 (01) : 33 - 41
  • [5] RESPONSE PROPERTIES OF TRIGEMINAL GANGLION-CELLS IN ADULT-RATS WITH NEONATAL INFRAORBITAL (IO) NERVE SECTIONS
    RENEHAN, WE
    JACQUIN, MF
    KLEIN, BG
    MOONEY, RD
    RHOADES, RW
    [J]. ANATOMICAL RECORD, 1985, 211 (03): : A159 - A159
  • [6] REORGANIZATION OF THE PERIPHERAL PROJECTIONS OF THE TRIGEMINAL GANGLION FOLLOWING NEONATAL TRANSECTION OF THE INFRAORBITAL NERVE
    RHOADES, RW
    CHIAIA, NL
    MOONEY, RD
    KLEIN, BG
    RENEHAN, WE
    JACQUIN, MF
    [J]. SOMATOSENSORY RESEARCH, 1987, 5 (01): : 35 - 62
  • [7] CENTRAL PROJECTIONS OF THE NORMAL AND REGENERATE INFRAORBITAL NERVE IN ADULT-RATS SUBJECTED TO NEONATAL UNILATERAL INFRAORBITAL LESIONS - A TRANSGANGLIONIC HORSERADISH-PEROXIDASE STUDY
    JACQUIN, MF
    RHOADES, RW
    [J]. BRAIN RESEARCH, 1983, 269 (01) : 137 - 144
  • [8] Behavioral study of non-evoked orofacial pain following different types of infraorbital nerve injury in rats
    Deseure, Kristof
    Hans, Guy
    [J]. PHYSIOLOGY & BEHAVIOR, 2015, 138 : 292 - 296
  • [9] Rapid shifts in receptive fields of cells in trigeminal subnucleus interpolaris following infraorbital nerve transection in adult rats
    Klein, BG
    White, CF
    Duffin, JR
    [J]. BRAIN RESEARCH, 1998, 779 (1-2) : 136 - 148
  • [10] Apoptotic cascade of neurons in the subcortical sensory relay nuclei following the neonatal infraorbital nerve transection
    Sugimoto, T
    Xiao, C
    Takeyama, A
    He, YF
    Takano-Yamamoto, T
    Ichikawa, H
    [J]. BRAIN RESEARCH, 1999, 824 (02) : 284 - 290
12345