SITES OF PHOTOSENSITIZATION BY PROTOPORPHYRIN AND TIN PROTOPORPHYRIN IN LEUKEMIA-L1210 CELLS

被引:6
|
作者
KESSEL, D [1 ]
SCHULZ, V [1 ]
机构
[1] WAYNE STATE UNIV,SCH MED,DEPT MED,DETROIT,MI 48201
关键词
Fluorescence; photosensitization; porphyrins;
D O I
10.1016/1011-1344(90)85077-A
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Studies with protoporphyrin (PP) and tin protoporphyrin (SnPP) were carried out to assess the effects of tin insertion on the sites of dye localization. Fluorescence emission spectra and studies on the sites of photodamage were consistent with a concentration of PP at membrane loci. In contrast, SnPP photodamage involved an intracellular site. © 1990.
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页码:87 / 92
页数:6
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