TRISOMY-4 IN ACUTE NONLYMPHOCYTIC LEUKEMIA - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE

被引：9
|
作者：
DONTI, E
MACCARI, A
TABILIO, A
ARDISIA, C
CAMPANARI, N
DONTI, GV
机构：
[1] UNIV PERUGIA,DEPT INTERNAL MED 1,I-06100 PERUGIA,ITALY
[2] UNIV PERUGIA,DEPT INTERNAL MED 2,I-06100 PERUGIA,ITALY
[3] UNIV PERUGIA,INST HEMATOL,I-06100 PERUGIA,ITALY
来源：
CANCER GENETICS AND CYTOGENETICS | 1992年 / 60卷 / 02期
关键词：
D O I：
10.1016/0165-4608(92)90018-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Two patients with M2 subtype of acute nonlymphocytic leukemia (ANLL) and trisomy 4 as a primary karyotype change are described. The abnormality was observed in 100% of bone marrow (BM) metaphases in both cases. It appeared alone in one case and was associated with trisomy 13 in 94% of metaphases in the other, These are the second and third cases of ANLL with trisomy 4 documented in Italy. Neither patient appears to have incurred any environmental or therapeutic insult.
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页码：195 / 197
页数：3
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