A MOUSE ATTENUATED MUTANT OF JUNIN VIRUS WITH AN ALTERED ENVELOPE GLYCOPROTEIN

被引：13
|
作者：
SCOLARO, LA [1 ]
MERSICH, SE [1 ]
DAMONTE, EB [1 ]
机构：
[1] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,DEPT QUIM BIOL,VIROL LAB,PABELLON 2,PISO 4,RA-1428 BUENOS AIRES,ARGENTINA
来源：
ARCHIVES OF VIROLOGY | 1990年 / 111卷 / 3-4期
关键词：
D O I：
10.1007/BF01311059
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag.
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收藏
页码：257 / 262
页数：6
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