Comorbid Psychopathology, Substance Use, and Treatment Outcomes: A Follow-Up of Inpatient Substance Users in Cape Town, South Africa

Comorbid psychopathology in substance users is thought to be associated with poor substance use treatment outcomes. This study followed up with 95 substance users after inpatient treatment for substance use. Males and patients who were single were more likely to complete treatment. Females were more likely than males to relapse or not complete treatment. No statistically significant associations were found between comorbid psychopathology, substances of use, and treatment outcomes. Primary users of crystal methamphetamine were marginally more likely than primary users of other substances not to complete treatment (OR = 0.291; p = .062). Major depression was marginally associated with decreased odds of relapse (OR = 0.346; p = .076). Further investigation is needed to explore the factors that influence treatment completion and relapse in female inpatients.