This paper describes similar congenital cardiac anomalies in 2 half sibling Jersey calves. Both calves had ventricular septal defects with dextraposition of the aorta and hypertrophy of the right ventricle, consistent with Eisenmenger's complex. One of the calves also had patent foramen ovale. The 2 calves had been sired by the same bull, and collateral relationships existed between the sire and the 2 dams.