FOTEMUSTINE IN PATIENTS WITH RELAPSING MALIGNANT GLIOMAS - A PHASE-II TRIAL

被引：0
|
作者：
PUNT, CJA
STAMATAKIS, L
GERARD, B
机构：
[1] INST RECH INT SERV,BRUSSELS,BELGIUM
[2] CTR HOSP TIVOLI,LA LOUVIERE,BELGIUM
来源：
ONCOLOGY REPORTS | 1995年 / 2卷 / 02期
关键词：
BRAIN TUMORS; GLIOMA; ASTROCYTOMA; GLIOBLASTOMA MULTIFORME; CHEMOTHERAPY; FOTEMUSTINE;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Eleven patients with relapsing malignant glioma were treated with fotemustine chemotherapy, a new nitrosourea derivative. One partial response of 13 months duration occurred, resulting in a marked improvement of the quality of life of the patient. Seven patients had stable disease for a median duration of 5 months. Median survival from inclusion in the study was 6 months. Toxicity was mainly hematologic and manageable. We confirm that fotemustine has some activity in patients with relapsing malignant glioma.
引用
收藏
页码：307 / 308
页数：2
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