CYCLANDELATE IN DIABETIC NEUROPATHY - A DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, CROSS-OVER STUDY

被引：0

作者：

HEIMANS, JJ ^{[1
]}

DRUKARCH, B ^{[1
]}

MATTHAEI, I ^{[1
]}

IJFF, GA ^{[1
]}

BERTELSMANN, FW ^{[1
]}

STRIJERS, RLM ^{[1
]}

NAUTA, J ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM HOSP,DEPT THEORY MED,1007 MB AMSTERDAM,NETHERLANDS

来源：

ACTA NEUROLOGICA SCANDINAVICA | 1991年 / 84卷 / 06期

关键词：

DIABETIC NEUROPATHY; THERAPY; CYCLANDELATE;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cyclandelate has the ability to improve the rheological properties of the blood and therefore may improve blood supply of peripheral nerves. Previous studies in diabetic neuropathy have shown beneficial effects of the drug. We performed a double-blind, placebo-controlled, cross-over study in 40 diabetic patients with cyclandelate in a dose of 1600 mg daily. Motor and sensory nerve conduction velocities, late responses, thermal discrimination thresholds, vibration perception thresholds and pain scores were studied. We were not able to show any positive effect of the drug and therefore conclude that cyclandelate is not effective in the treatment of diabetic neuropathy.

引用

页码：483 / 486

页数：4

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