PIXE MICROANALYSIS OF TRACE-ELEMENTS OF THE NORMOXIC, ISCHEMIC AND REPERFUSED RAT-HEART

被引：5
|
作者：
VERHOEF, BAW
FREDERIK, PM
BOMANS, PHH
VANDERVUSSE, GJ
MUTSAERS, PHA
DELEPPER, ECP
DEVOIGT, MJA
机构：
[1] UNIV LIMBURG, CARDIOVASC RES INST MAASTRICHT, DEPT PATHOL, EM UNIT, 6200 MD MAASTRICHT, NETHERLANDS
[2] EINDHOVEN UNIV TECHNOL, DEPT PHYS, CYCLOTRON LAB, 5600 MB EINDHOVEN, NETHERLANDS
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1995年 / 104卷 / 1-4期
关键词：
D O I：
10.1016/0168-583X(95)00420-3
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
Via PIXE with a 3 x 3 mu m(2) proton microbeam spatial distributions of Na, Mg, P, S, K, Ca and Fe were measured in 50 x 50 mu m(2) areas of rat heart, sliced into 10-15 mu m thick cryosections. The hearts were subjected to normal perfusion, ischemia and reperfusion. Substantial changes were found in tissue after 40 min of reperfusion, where locally elevated Ca levels and decreased K levels were observed. For assessment of artefacts due to sample preparation and handling also electron microscopy was used.
引用
收藏
页码：311 / 316
页数：6
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