AGING AND GENETIC-CONTROL OF IMMUNE RESPONSIVENESS

被引：8
|
作者：
DORIA, G
FRASCA, D
机构：
[1] Laboratory of Immunology, AMB-EFF, ENEA Casaccia, Rome
来源：
IMMUNOLOGY LETTERS | 1994年 / 40卷 / 03期
关键词：
EXOGENOUS ANTIGEN; AUTOIMMUNITY; INTERLEUKIN-2; CELL PROLIFERATION; CELL DIFFERENTIATION; THYMUS;
D O I：
10.1016/0165-2478(94)00061-1
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focused on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].
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页码：231 / 233
页数：3
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