Outcomes Assessment of Transoral Laser Microsurgery for T1 and T2 Glottic Cancer at the Ho Chi Minh City Ear-Nose-Throat Hospital

Introduction: Transoral Laser Microsurgery (TLM) has been accepted as a major treatment modality for early glottic carcinoma (T1, T2), with well-known advantages over Radiation Therapy (RT) and open partial laryngectomy. Aim: To evaluate the oncological outcomes in a consecutive series of early glottic carcinomas treated with TLM as a single-modality therapy. Materials and Methods: The study was conducted using the medical records of 32 consecutive patients who underwent TLMs and postoperative follow-ups. We only evaluated the oncological outcomes for 1-year disease-free survival and the organ preservation rate. The prognostic values of the related clinicopathological factors were evaluated using univariate analysis. Results: Of the 32 patients, 31 were males and one was a female, with an average age of 61 years. The tumours were treated by cordectomy types IV (78.1%), Va (18.8%) and Vb (3.3%). The voice outcomes were assessed using the Voice Handicap Index scale, which showed that 8 patients had normal voices and 22 had mild changes. Only 2 had moderate-to- severe voice changes. The mean hospitalization period was 4.4 days (range 3-7 days). For resection margins, as reported by the pathologist, 31 cases (96.9%) had negative margins and 1 case (3.1%) had a positive margin. Conclusion: Laser surgery has very good oncological outcomes for T1 and T2 glottic cancer with the highly proportion of negative margins and the voice outcomes is normal or mild changed.