Screening for CGG trinucleotide repeat expansion in the fragile X mental retardation 1 gene in schizophrenic patients

被引：0

作者：

Jonsson, E

Bjorck, E

Wahlstrom, J

Gustavsson, P

Sedvall, G

机构：

[1] KAROLINSKA HOSP, DEPT CLIN NEUROSCI, PSYCHIAT SECT, S-17176 STOCKHOLM, SWEDEN

[2] EAST HOSP, DEPT CLIN GENET, S-41685 GOTHENBURG, SWEDEN

来源：

PSYCHIATRIC GENETICS | 1995年 / 5卷 / 04期

关键词：

fragile X; Hodgkin's disease; schizophrenia;

D O I：

暂无

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Patients diagnosed using DSM-III-R criteria as having schizophrenia and other related disorders (n = 128) were assessed for CGG trinucleotide repeat expansion in the fragile X mental retardation 1 (FMR-1) gene. One subject, a woman with schizophreniform disorder, was found to have a premutation of the gene. Her case report is given. The present investigation supports the view that mutation or premutation of the FMR-1 gene is not of importance for the aetiology of the vast majority of schizophrenic patients.

引用

页码：157 / 160

页数：4

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