RECOMBINANT ERYTHROPOIETIN AS TREATMENT FOR THE LATE HYPOREGENERATIVE ANEMIA OF RH HEMOLYTIC-DISEASE

被引:0
|
作者
OHLS, RK [1 ]
WIRKUS, PE [1 ]
CHRISTENSEN, RD [1 ]
机构
[1] UNIV UTAH,SCH MED,DIV NEONATOL,SALT LAKE CITY,UT 84132
关键词
ERYTHROPOIETIN; RH HEMOLYTIC DISEASE; ANEMIA; NEONATES;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Infants with Rh hemolytic disease can develop a ''late'' anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.
引用
收藏
页码:678 / 680
页数:3
相关论文
共 50 条
  • [1] LATE HYPOREGENERATIVE ANEMIA IN RH HEMOLYTIC-DISEASE
    KOENIG, JM
    ASHTON, RD
    DEVORE, GR
    CHRISTENSEN, RD
    JOURNAL OF PEDIATRICS, 1989, 115 (02): : 315 - 318
  • [2] Hyporegenerative anemia associated with Rh hemolytic disease: Treatment failure of recombinant erythropoietin
    Pessler, F
    Hart, D
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2002, 24 (08) : 689 - 693
  • [3] RECOMBINANT ERYTHROPOIETIN AS AN ALTERNATIVE TO TRANSFUSION FOR THE LATE ANEMIA OF RH HEMOLYTIC-DISEASE
    OHLS, RK
    CHRISTENSEN, RD
    CLINICAL RESEARCH, 1992, 40 (01): : A65 - A65
  • [4] Recombinant erythropoietin as treatment for hyporegenerative anemia following hemolytic disease of the newborn
    Donato, Hugo
    Bacciedoni, Viviana
    Garcia, Cecilia
    Schvartzman, Gabriel
    Vain, Nestor
    ARCHIVOS ARGENTINOS DE PEDIATRIA, 2009, 107 (02): : 119 - 125
  • [5] Erythropoietin as treatment for late hyporegenerative anemia in neonates with Rh hemolytic disease after in utero exchange transfusion
    Nicaise, C
    Gire, C
    Casha, P
    d'Ercole, C
    Chau, C
    Palix, C
    FETAL DIAGNOSIS AND THERAPY, 2002, 17 (01) : 22 - 24
  • [6] HYPOREGENERATIVE ANEMIA ASSOCIATED WITH INTRAUTERINE TRANSFUSION IN RHESUS HEMOLYTIC-DISEASE
    THORP, JA
    OCONNOR, T
    CALLENBACH, J
    COHEN, GR
    YEAST, JD
    ALBIN, J
    PLAPP, F
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1991, 165 (01) : 79 - 81
  • [7] Late hyporegenerative anemia in neonates with rhesus hemolytic disease
    Al-Alaiyan, S
    Al Omran, A
    JOURNAL OF PERINATAL MEDICINE, 1999, 27 (02) : 112 - 115
  • [8] SUPPRESSION OF ERYTHROPOIESIS BY INTRAUTERINE TRANSFUSIONS IN HEMOLYTIC-DISEASE OF THE NEWBORN - USE OF ERYTHROPOIETIN TO TREAT THE LATE ANEMIA
    SCARADAVOU, A
    INGLIS, S
    PETERSON, P
    DUNNE, J
    CHERVENAK, F
    BUSSEL, J
    JOURNAL OF PEDIATRICS, 1993, 123 (02): : 279 - 284
  • [9] PREVENTING RH HEMOLYTIC-DISEASE
    WEINSTEIN, L
    ARIZONA MEDICINE, 1980, 37 (01) : 28 - 28
  • [10] THE DISCOVERY OF RH HEMOLYTIC-DISEASE
    LEVINE, P
    VOX SANGUINIS, 1984, 47 (02) : 187 - 190