A rare case of glycine encephalopathy unveiled by valproate therapy

被引：3

作者：

Subramanian, Velusamy ^{[1
]}

Kadiyala, Pramila ^{[3
]}

Hariharan, Praveen ^{[4
]}

Neeraj, E. ^{[2
]}

机构：

[1] Stanley Med Coll, Dept Paediat Neurol, Inst Social Paediat, Madras, Tamil Nadu, India

[2] Stanley Med Coll, Dept Paediat, Inst Social Paediat, Madras, Tamil Nadu, India

[3] Madras Med Coll & Govt Gen Hosp, Dept Biochem, Inst Child Hlth, Madras, Tamil Nadu, India

[4] Stanley Med Coll, Chennai, Tamil Nadu, India

来源：

JOURNAL OF PEDIATRIC NEUROSCIENCES | 2015年 / 10卷 / 02期

关键词：

Glycine encephalopathy; nonketotic hyperglycinemia; organic acidemia; recurrent seizures; valproate;

D O I：

10.4103/1817-1745.159200

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Glycine encephalopathy (GE) or nonketotic hyperglycinemia is an autosomal recessive disorder due to a primary defect in glycine cleavage enzyme system. It is characterized by elevated levels of glycine in plasma and cerebrospinal fluid usually presenting with seizures, hypotonia, and developmental delay. In our case, paradoxical increase in seizure frequency on starting sodium valproate led us to diagnose GE.

引用

页码：143 / 145

页数：3

共 50 条

[1] A RARE CASE OF VALPROATE INDUCED HYPERAMMONEMIC ENCEPHALOPATHY(VHE)
Podugu, Amareshwar
Adam, Mohamad
Chakka, Asha
JOURNAL OF GENERAL INTERNAL MEDICINE, 2013, 28 : S271 - S271
[2] Rare Case of Valproate-Induced Hyperammonemic Encephalopathy
Kunduru, Mahathi
Mandal, Shobha
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2024, 119 (10S): : S2945 - S2945
[3] A Rare Case of Valproate-Induced Encephalopathy Requiring Hemofiltration
Myat, Thin
Win, Min
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2019, 114 : S1260 - S1260
[4] A case of hyperammonemic encephalopathy after 11 years of valproate therapy
Stewart, Jonathan T.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2008, 28 (03) : 361 - 362
[5] ABNORMAL-METABOLISM OF CARNITINE AND VALPROATE IN A CASE OF ACUTE ENCEPHALOPATHY DURING CHRONIC VALPROATE THERAPY
MURAKAMI, K
SUGIMOTO, T
NISHIDA, N
KOBAYASHI, Y
KUHARA, T
MATSUMOTO, I
BRAIN & DEVELOPMENT, 1992, 14 (03): : 178 - 181
[6] A case of glycine encephalopathy
Pereiro, N.
Lava, S.
McDougall, J.
Gautschi, M.
Perret-Hoigne, E.
SWISS MEDICAL WEEKLY, 2015, 145 : 38 - 38
[7] A STRATEGY FOR GLYCINE ENCEPHALOPATHY THERAPY
MENDELSON, IS
JOURNAL OF MENTAL DEFICIENCY RESEARCH, 1982, 26 (JUN): : 107 - 110
[8] A Case of Valproate Induced Hyperammonemic Encephalopathy
Tarafdar, Surjit
Slee, Mark
Ameer, Faisal
Doogue, Matt
CASE REPORTS IN MEDICINE, 2011, 2011
[9] A case of valproate-induced encephalopathy
Hong, Lin
Schutz, Jedda
Nance, Michael
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2012, 46 (12): : 1200 - 1201
[10] Valproate semisodiumHyperammonaemic encephalopathy: case report
Reactions Weekly, 2014, 1483 (1) : 95 - 95

← 1 2 3 4 5 →