GENOTOXICITY OF POLYCYCLIC AROMATIC-HYDROCARBONS IN ESCHERICHIA-COLI PQ37

被引：95
|
作者：
MERSCHSUNDERMANN, V
MOCHAYEDI, S
KEVEKORDES, S
机构：
来源：
MUTATION RESEARCH | 1992年 / 278卷 / 01期
关键词：
SOS CHROMOTEST; POLYCYCLIC AROMATIC HYDROCARBONS; GENOTOXICITY;
D O I：
10.1016/0165-1218(92)90279-9
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
In the present investigation, 32 polycyclic aromatic hydrocarbons (PAHs) were tested for genotoxicity in E. coli PQ37 using the standard tube assay of the SOS chromotest. PAHs such as benzo[ghi]fluoranthene, benzo[j]fluoranthene, benzo[a]pyrene, chrysene, dibenzo[a,l]pyrene, fluoranthene and triphenylene exhibited high genotoxicity when incubated in the presence of an exogenous metabolic activation mixture. The results were compared to those obtained with the Salmonella/microsome test.
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页码：1 / 9
页数：9
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