Borderline ovarian tumors

被引：0
|
作者：
Wenners, A. [1 ]
Bauer, M. [1 ]
Strauss, A. [1 ]
Hilpert, F. [1 ]
机构：
[1] Univ Klinikum Schleswig Holstein, Klin Gynakol & Geburtshilfe, Campus Kiel,Arnold Heller Str 3,Haus 24, D-24105 Kiel, Germany
来源：
GYNAKOLOGE | 2012年 / 45卷 / 04期
关键词：
Oncogenic mutations; Cytoreduction; Fertility; Metastases; Tumor biology;
D O I：
10.1007/s00129-012-2959-z
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Borderline ovarian tumors (BOT) are clinically and morphologically defined as being between cell-specific benign and malignant ovarian tumors. The hypothesis of a continuous carcinogenesis is theoretically supported by a model of the genesis of malignant ovarian tumors. The transferability to various ovarian malignancies has not yet been finally explained but the model also has relevant implications for the management of BUT. Women in child-bearing age are disproportionally more often affected by BOT so that the question of therapy is basically concerned with maintaining fertility. In addition to age and FIGO stage, cytoreduction by the primary operation seems to be the deciding prognostic factor and the residual postoperative tumor mass is an independent prognosis factor. In addition to these aspects the current situation with respect to BOT and prognosis will be discussed.
引用
收藏
页码：296 / 303
页数：8
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