FUNCTIONAL CLONING OF A DICTYOSTELIUM-DISCOIDEUM CDNA-ENCODING GMP SYNTHETASE

被引：0

作者：

CAMPAGNE, MMV

FRANKE, J

KESSIN, RH

机构：

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 1991年 / 266卷 / 25期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A functional cloning procedure has been used to recover a cDNA coding for the GMP synthetase of Dictyostelium discoideum. The enzyme is encoded by a single gene, which is actively transcribed during growth, but not during development. The open reading frame encodes a protein of 718 amino acids with a predicted molecular mass of 79.6 kDa. The Dictyostelium enzyme has extensive homology with the GMP synthetase of Escherichia coli and regional homology to other glutamine amidotransferases.

引用

页码：16448 / 16452

页数：5

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