DETERMINATION OF ANTIBODIES TO PERTUSSIS TOXIN IN WORKING REFERENCE PREPARATIONS OF ANTI-PERTUSSIS SERA FROM VARIOUS NATIONAL CONTROL LABORATORIES

被引：8

作者：

RELYVELD, E

OATO, NH

HUET, M

GUPTA, RK

机构：

[1] MASSACHUSETTS PUBL HLTH BIOL LABS,BOSTON,MA 02130

[2] INST BOUISSON BETRAND,F-34090 MONTPELLIER,FRANCE

来源：

BIOLOGICALS | 1992年 / 20卷 / 01期

关键词：

D O I：

10.1016/S1045-1056(05)80009-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Working reference preparations of anti-pertussis sera from various National Control Laboratories were assayed for anti-PT antibodies by standardized ELISA and toxin neutralization (Nt) test. Both the ELISA and Nt tests gave highly reproducible results for various preparations when these preparations were assayed repeatedly on different days. Various working reference preparations were assigned units against the proposed International standard for anti-pertussis serum (JNIH-10) assuming its unitage of 250. Assigning unitage to various preparations would help in comparing results of ELISA and Nt tests for anti-PT antibodies reported in various studies. © 1992 The International Association of Biological Standardization.

引用

页码：67 / 71

页数：5

共 9 条

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