Polycystic Ovary Syndrome and Insulin Resistance

Polycystic ovary syndrome is a complex and heterogeneous disease that involves menstrual dysfunction and reproductive difficulty as well as metabolic problems. Therefore, it was proposed that insulin resistance is the pathophysiological basis for this syndrome. Insulin resistance, as a metabolic disorder linked to anovulation, should be studied in patients who meet with a gynecologist. For this purpose, simple methods to quantify insulin sensitivity are available, and we propose reasonable treatment with dietary or pharmaceutical measures to improve not only the metabolic changes but also clinical hyperandrogenism and fertility.