BOTULINUM TOXIN IN THE TREATMENT OF CEREBRAL-PALSY

被引：56
|
作者：
DENISLIC, M [1 ]
MEH, D [1 ]
机构：
[1] UNIV LJUBLJANA,SCH MED,INST ANAT,LJUBLJANA 61105,SLOVENIA
来源：
NEUROPEDIATRICS | 1995年 / 26卷 / 05期
关键词：
BOTULINUM TOXIN; CEREBRAL PALSY; DYNAMIC CONTRACTURES; SKILLED MOVEMENTS;
D O I：
10.1055/s-2007-979765
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This paper reports the results of botulinum toxin A treatment in 13 children with cerebral palsy. All patients except one exhibited dynamic deformities in one hand or foot and changes in muscle tone of corticospinal and extrapyramidal origin. The primary purpose of the treatment was to improve the impaired skilled movements which resulted from dystonic limb posture and were the most disabling symptoms in the group studied. The study showed that the botulinum toxin treatment produced a significant improvement in functional disability in terms of amelioration of skilled hand movements and foot posture (p < 0.01). The injections took effect a few days after dystonic muscle infiltration, and the mean duration of improvement was 3.1 months (2.0 - 4.0 months). Side effects were negligible and transient; transitory muscle weakness was the most frequent. Botulinum toxin A provides a safe and effective adjuvant treatment of dystonic skilled movements and gait disorders in children with cerebral palsy
引用
收藏
页码：249 / 252
页数：4
相关论文
共 50 条
  • [1] BOTULINUM TOXIN-A IN MANAGEMENT OF CEREBRAL-PALSY
    CALDERONGONZALEZ, R
    CALDERONSEPULVEDA, R
    RINCONREYES, M
    GARCIARAMIREZ, J
    MINOARANGO, E
    [J]. PEDIATRIC NEUROLOGY, 1994, 10 (04) : 284 - 288
  • [2] USE OF BOTULINUM TOXIN FOR ADDUCTOR SPASTICITY IN CEREBRAL-PALSY
    SINGH, B
    SHAHWAN, SA
    MILLER, VS
    RIELA, AR
    [J]. ANNALS OF NEUROLOGY, 1994, 36 (03) : 513 - 513
  • [3] Botulinum toxin as treatment of cerebral palsy
    PascualPascual, SI
    deMuniain, PS
    Roche, MC
    PascualCastroviejo, I
    [J]. REVISTA DE NEUROLOGIA, 1997, 25 (145) : 1369 - 1375
  • [4] Botulinum toxin A in the treatment of cerebral palsy
    Kanovsky, P
    [J]. PERIODICUM BIOLOGORUM, 2002, 104 (01) : 39 - 42
  • [5] BOTULINUM TOXIN IN THE MANAGEMENT OF THE LOWER-LIMB IN CEREBRAL-PALSY
    COSGROVE, AP
    CORRY, IS
    GRAHAM, HK
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1994, 36 (05): : 386 - 396
  • [6] MANAGEMENT OF CEREBRAL-PALSY WITH BOTULINUM-A TOXIN - PRELIMINARY INVESTIGATION
    KOMAN, LA
    MOONEY, JF
    SMITH, B
    GOODMAN, A
    MULVANEY, T
    [J]. JOURNAL OF PEDIATRIC ORTHOPAEDICS, 1993, 13 (04) : 489 - 495
  • [7] MANAGEMENT OF SPASTICITY IN CEREBRAL-PALSY WITH LOCAL APPLICATION OF BOTULINUM-TOXIN-A
    BENETIN, J
    KUCHAR, M
    [J]. CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 1995, 58 (05) : 252 - 253
  • [8] Experience with botulinum toxin in the treatment of cerebral palsy
    Arens, LJ
    Leary, PM
    Goldschmidt, RB
    [J]. SOUTH AFRICAN MEDICAL JOURNAL, 1997, 87 (08): : 1001 - 1003
  • [9] Botulinum toxin treatment in children with cerebral palsy
    Terebessy Tamas
    Domos Gyula
    Hever Dalma
    Horvath Nikoletta
    Kiss Sandor
    Szoke Gyorgy
    [J]. ORVOSI HETILAP, 2019, 160 (28) : 1105 - 1111
  • [10] Botulinum toxin A in treatment of cerebral palsy spasticity
    Carrelet, P
    Bollini, G
    Mancini, J
    Chabrol, B
    [J]. ARCHIVES DE PEDIATRIE, 2002, 9 (09): : 928 - 933
12345