Diagnostic Accuracy of BNP Levels in Detection of Heart Failure

被引:0
|
作者
Nauman, E.
Nisar, A.
Munir, A. R.
Mubasher, A. S.
机构
关键词
Heart failure; B-type natriuretic peptide; Left ventricular failure; Echocardiography;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Evaluation of serum Brain Natriuretic Peptide levels as screening test in the diagnosis of left ventricular failure or congestive heart failure Material and methods: This cross-sectional survey was conducted at the Department of Medicine, Nishtar Hospital and Ch Parvez Ellahi Institute of Cardiology Multan from Feb 2006 to August 2006. A total of 50 patients were studied. Sampling was performed by non probability convenient type sampling technique. Results: Out of the 50 patients, 47(94%) patients had ejection fraction of less than 45% and were diagnosed as cardiac failure, as confirmed by echocardiography. Among these cases BNP levels were found to be elevated in 36(72%) patients, whereas in 11 (22%) cases, BNP levels were falsely negative. Only 3 patients (6%) in whom initial clinical diagnosis was heart failure, were later found to have negative echocardiography (EF > 45%). Two patients (4%) with negative echocardiography (EF > 45%), had the BNP levels also negative i.e. below the cut-off point, whereas BNP was falsely positive in 1 patient Sensitivity and specificity of BNP (by ELISA) was found to be 80% and 66% respectively and accuracy was 80%. Conclusion: BNP measurements in the blood, is a new technique to diagnose heart failure. The clinical sensitivity and specificity of BNP (by ELISA) was although lower than echocardiography but it can be a good alternative for echocardiography.
引用
收藏
页码:129 / 133
页数:5
相关论文
共 50 条
  • [1] Comparison of the diagnostic accuracy of BNP and NT-proBNP in acute and chronic heart failure
    Mueller, Christian
    [J]. CLINICAL CHEMISTRY, 2007, 53 (09) : 1719 - 1720
  • [2] Diagnostic value of BNP in diastolic heart failure
    Eroglu, Serpil
    Bozbas, Huseyin
    Muderrisoglu, Haldun
    [J]. BIOCHEMIA MEDICA, 2008, 18 (02) : 183 - 192
  • [3] Comparison between BNP and NT-proBNP diagnostic accuracy for early diagnosis of heart failure
    Emdin, M.
    Fontana, M.
    Giannoni, A.
    Gabutti, A.
    Mammini, C.
    Poletti, R.
    Prontera, C.
    Zyw, L.
    Clerico, A.
    Passino, C.
    [J]. EUROPEAN HEART JOURNAL, 2007, 28 : 306 - 306
  • [4] BNP, ECG and echocardiography in the detection of heart failure
    Watson, ID
    Stephens, B
    Perry, Y
    Howard, A
    Lewis, C
    Rodrigues, E
    [J]. CLINICA CHIMICA ACTA, 2005, 355 : S122 - S122
  • [5] Use of BNP levels in monitoring hospitalized heart failure patients with heart failure
    Maisel, AS
    [J]. HEART FAILURE REVIEWS, 2003, 8 (04) : 339 - 344
  • [6] Use of BNP Levels in Monitoring Hospitalized Heart Failure Patients with Heart Failure
    Alan S. Maisel
    [J]. Heart Failure Reviews, 2003, 8 : 339 - 344
  • [7] Diagnostic accuracy of left atrial remodelling and natriuretic peptide levels for preclinical heart failure
    Tsai, Jui-Peng
    Sung, Kuo-Tzu
    Su, Cheng-Huang
    Lai, Yau-Huei
    Kuo, Jen-Yuan
    Yun, Chun-Ho
    Yen, Chih-Hsuan
    Hou, Charles Zia-Yin
    Wu, Tung-Hsin
    Peng, Ming-Cheng
    Hung, Ta-Chuan
    Yeh, Hung-, I
    Hung, Chung-Lieh
    [J]. ESC HEART FAILURE, 2019, 6 (04): : 723 - 732
  • [8] Role of BNP Levels on the Prognosis of Decompensated Advanced Heart Failure
    Pereira-Barretto, Antonio Carlos
    Del Carlo, Carlos Henrique
    Cardoso, Juliano Novaes
    Ochiai, Marcelo Eid
    Lima, Marcelo Villaca
    Curiati, Milena Cardoso
    Scipioni, Airton Roberto
    Franchini Ramires, Jose Antonio
    [J]. ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 2013, 100 (03) : 281 - 287
  • [9] Diagnostic accuracy of natriuretic peptides for heart failure
    Battaglia, M
    Bachmann, LM
    Egger, M
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (06) : 704 - 704
  • [10] Impact of the history of congestive heart failure on accuracy of BNP in the emergency diagnosis of heart failure: Results from the breathing not properly (BNP) multinational study
    Strunk, A
    Bhalla, V
    Clopton, P
    Nowak, RM
    McCord, J
    Hollander, JE
    Storrow, AB
    Abraham, WT
    Wu, AHB
    Steg, G
    Perez, A
    Kazanegra, R
    Herrmann, HC
    Aumont, MC
    McCullough, PA
    Maisel, A
    [J]. JOURNAL OF CARDIAC FAILURE, 2004, 10 (04) : S50 - S50