Anti Cariogenic Effect of Terminalia Chebula

被引:8
|
作者
Rekha, Vidhya [1 ]
Jayamathi [2 ]
RamaKrishnan [3 ]
Vijayalakshmi, Devaki [4 ]
Prabu [1 ]
Kumar, Nandha [5 ]
Manipal, Sunayana [1 ]
Keerthidaa [6 ]
机构
[1] SRM Dent Coll, Dept Publ Hlth Dent, Madras, Tamil Nadu, India
[2] Meenakshi Ammal Dent Coll, Dept Biochem, Madras, Tamil Nadu, India
[3] Meenakshi Ammal Dent Coll, Dept Periodont, Madras, Tamil Nadu, India
[4] Meenakshi Ammal Dent Coll, Dept Orthodont, Madras, Tamil Nadu, India
[5] Indira Gandhi Inst Dent Sci, Dept Orthodont, Pondicherry, India
[6] Meenakshi Ammal Dent Coll, Madras, Tamil Nadu, India
关键词
Antimicrobial activity; Catalase test; Dental caries; Terminalia chebula;
D O I
10.7860/JCDR/2014/9844.4765
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Terminalia chebula is one of the traditional medicines used in the treatment of many diseases and possesses a wide variety of therapeutic activities. The aim of this study was to determine the antimicrobial properties of Terminalia chebula against oral pathogens related to caries. Materials and Methods: In this study, Antimicrobial activity was tested using Kirby bouer method by streaking. Total phenol and total flavonoid content were analysed. Twenty high caries risk patients were subjected to rinse aqueous extract of Terminalia chebula. Salivary samples were collected for pH and microbial screening. Oral pathogens were identified by qualitative biochemical analysis. Results: The total phenol content of extract was found to be 21.33 +/- 1.633 (mean +/- SD) and total flavonoids was found to be 23.17 +/- 2.317 (mean +/- SD). There was a gradual increase in pH till 45mts post-rinse when compared to pre-rinse was observed. Antimicrobial effect of Terminalia Chebula aganist microbes showed that there was a significant reduction between the prerinse and post-rinse samples. Conclusion: These promising findings suggested the presence of antimicrobial activity of Terminalia Chebula against oral pathogens and proven to be an effective alternate antimicrobial agent.
引用
收藏
页码:ZC51 / ZC54
页数:4
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