FRAGILE X-SYNDROME - THE MOLECULAR PICTURE COMES INTO FOCUS

被引：28
|
作者：
RICHARDS, RI
SUTHERLAND, GR
机构：
来源：
TRENDS IN GENETICS | 1992年 / 8卷 / 07期
关键词：
D O I：
10.1016/0168-9525(92)90124-M
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Fragile X syndrome is one of the most common human genetic diseases. It is characterized by a fragile site on the X chromosome, and the DNA that gives rise to the fragile site has now been cloned and characterized. This has resulted in the discovery of a new genetic element, a heritable unstable DNA sequence, and a new genetic mechanism, dynamic mutation.
引用
收藏
页码：249 / 255
页数：7
相关论文
共 50 条
  • [1] MOLECULAR ANALYSIS OF THE FRAGILE X-SYNDROME
    DAVIES, KE
    PATTERSON, M
    BELL, M
    KENWRICK, SJ
    [J]. JOURNAL OF MEDICAL GENETICS, 1988, 25 (02) : 129 - 129
  • [2] MOLECULAR ANALYSIS OF THE FRAGILE X-SYNDROME
    HIRST, MC
    KNIGHT, SM
    NAKAHORI, Y
    ROCHE, A
    DAVIES, KE
    [J]. JOURNAL OF INHERITED METABOLIC DISEASE, 1992, 15 (04) : 532 - 538
  • [3] MOLECULAR ANALYSIS OF THE FRAGILE X-SYNDROME
    KNIGHT, SJL
    HIRST, MC
    DAVIES, KE
    [J]. DISEASE MARKERS, 1992, 10 (01) : 1 - 5
  • [4] MOLECULAR GENETIC ADVANCES IN FRAGILE X-SYNDROME
    TARLETON, JC
    SAUL, RA
    [J]. JOURNAL OF PEDIATRICS, 1993, 122 (02): : 169 - 185
  • [5] Fragile X-Syndrome: Clinical and Molecular Studies
    Behery, Amal K.
    [J]. JOURNAL OF THE EGYPTIAN PUBLIC HEALTH ASSOCIATION, 2008, 83 (3-4): : 273 - 283
  • [6] FRAGILE X-SYNDROME
    TURNER, G
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1991, 49 (04) : 35 - 35
  • [7] FRAGILE X-SYNDROME
    REISS, AL
    FREUND, L
    [J]. BIOLOGICAL PSYCHIATRY, 1990, 27 (02) : 223 - 240
  • [8] THE FRAGILE X-SYNDROME
    DELGIUDICE, E
    POGGI, V
    SARTORIO, R
    CARROZZO, R
    ROMANO, A
    SIRONE, P
    FIORE, M
    [J]. RIVISTA ITALIANA DI PEDIATRIA-ITALIAN JOURNAL OF PEDIATRICS, 1986, 12 (04): : 442 - 444
  • [9] THE FRAGILE X-SYNDROME
    BUNDEY, S
    [J]. PRACTITIONER, 1987, 231 (1431) : 910 - &
  • [10] MOLECULAR PREDICTORS OF COGNITIVE FUNCTION IN FRAGILE X-SYNDROME
    ABRAMS, M
    FREUND, L
    REISS, AL
    [J]. BIOLOGICAL PSYCHIATRY, 1993, 33 (6A) : A161 - A161
12345