MECHANICAL PROBLEMS IN THE RECONSTRUCTION OF ANTERIOR CRUCIATE LIGAMENTS (MECHANICAL COMPATIBILITY BETWEEN LIVING TISSUES AND ARTIFICIAL MATERIALS)

A qualitative model on the remodeling of fibrous connective tissues is proposed, from which it follows that the dynamic component of tensile strain induces strengthening of tissues, and their static component induces lengthening of tissues. Based on these hypotheses, we examine the design rules for compliant prostheses, the use of which will enhance the growth and reorganization of reconstructed tissues enveloping the prostheses. We constructed artificial ligaments for rabbit anterior cruciate ligaments, and carried out animal experiments. Unfortunately, considerable inflammation responses were induced, for which wear debris was believed to be responsible.